خانه / دکتر محمدحسین صنعتی

دکتر محمدحسین صنعتی

MOHAMMAD H. SANATI

B.Sc.,Chem.;M.Sc.,Biochem.(I.R.I);

Ph.D.,Medical Biotechnology (Australia)

…………………………………………………………………………

 

Date and Place of Birth:         ۶ September, 1958; Ferdos, Iran

 

Address for Correspondence: National Institute for Genetic

Engineering and Biotechnology (NIGEB)

P.O.Box : ۱۴۱۵۵-۶۳۴۳, Tehran, Iran

Telephone Numbers:               + ۹۸ ۲۱ ۴۴۵۸۰۳۴۶ (work), +98 21 88905500 (home)

                                                +۹۸ ۹۱۲ ۲۷۵ ۵۳۹۲ (cell phone)

Facsimile Number:                  +۹۸ ۲۱ ۴۴۵۸۰۳۴۶

                   E-mail:                 mhsanati@yahoo.com

………………………………………………………………………

 

CURRENT SITUATION:

– Researcher, Medical Genetics Department, NIGEB,

 (Since March 1997).

……………………………………………………………

EDUCATIONAL QUALIFICATIONS:

۱۹۹۱-۱۹۹۶ Ph.D. (Biotechnology) at Biotechnology Research Group,

School of Biological and Environmental Sciences, Murdoch University, Perth, Western Australia

۱۹۸۵-۱۹۸۸: M.Sc. (Biochemistry), Biochemistry Department, School of

          Medical Sciences, Tarbiat Modarres University, Tehran, Iran

۱۹۷۷-۱۹۸۴:            B.Sc. (Chemistry), Chemistry Department, School of Sciences,

                   Ferdousi Uneversity, Mashhad, Iran

Topics of Thesis:

PhD:       Cloning and characterization of a novel mitochondrial               autoantigen involved in multiple sclerosis

MSc: Production of antibody against the Small Molecules

BSc: Isolation and purification of color pigments from plant leaves.

 

WORK EXPERIENCES:

۲۰۰۶- Until now: Researcher at the Medical Genetic Department, National Institute for Genetic Engineering and Biotechnology, Tehran, Iran.

۱۹۹۷ – ۲۰۰۵: President of the National Institute for Genetic Engineering and Biotechnology, Tehran, Iran.

۱۹۹۵: Part time research assistant (work on multiple sclerosis diseases), Murdoch University, Western Australia.

۱۹۹۶: Full time researcher in Murdoch University, production of recombinant monoclonal antibody against the Rizhoctomi Saloon antigens in “Phage Display System.

۱۹۹۴: Demonstrator (practical molecular biology for undergraduate students), Murdoch University, Western Australia.

 

a) Papers published in Scientific Journals:

۱۰۵. Zahra Lashgary,Ahmad Khodadadi,Yoginder Singh,Seyed Massoud Houshmand, Frouzandeh Mahjoubi,Prithviraj Sharma,Shweta Singh,Mahtab Seyedin, Amit Srivastava,Mirtra Ataee,Zeinab Sadat Mohammadi,Nima Rezaei, Rameshwar N.K.Bamezai & Mohammad Hossein Sanati, Y chromosome diversity among the Iranian religious groups: a reservoir of genetic variation, Annals of human Biology, In Press.

۱۰۴. Fazeli AS, Nasrabadi D, Sanati MH, Pouya A, Ibrahim SM, Baharvand H, Salekdeh GH.

Proteome analysis of brain in murine experimental autoimmune encephalomyelitis. Proteomics,

 ۲۰۱۰ Aug;10(15):2822-32.

۱۰۳٫ Alasti F, Peeters N, Wuyts W, Sanati MH, Van Camp G. Novel human pathological mutations. Gene symbol: SLC26A4. Disease: Deafness, non-syndromic, autosomal recessive.

Hum Genet. 2010 Jan;127(1):116.

 

۱۰۲٫ Sareh Asadi, Mohammad Javan, Abolhassan Ahmadiani, Mohammad Hossein

Sanati, Alternative splicing in the synaptic protein interaction site of rat Cav2.2

(α۱B) calcium channels: Changes induced by chronic inflammatory pain, J Mol Neurosci. ۲۰۰۹ Sep; 39(1-2):40-8. Epub 2009 Jan 6.

 

۱۰۱٫ Mehrizi AA, Zakeri S, Salmanian AH, Sanati MH, Djadid ND, IgG subclasses pattern and high-avidity antibody to the C-terminal region of merozoite surface protein 1 of Plasmodium vivax in an unstable hypoendemic region in Iran, Acta Trop. ۲۰۰۹ Oct;112(1):1-7. Epub 2009 May 29.

 

۱۰۰٫ Isaian A, Bogdanova NV, Houshmand M, Movahadi M, Agamohammadi A, Rezaei N, Atarod L, Sadeghi-Shabestari M, Tonekaboni SH, Chavoshzadeh Z, Hassani SM, Mirfakhrai R, Cheraghi T, Kalantari N, Ataei M, Dork-BousT, Sanati MH, BAK, BAX, and NBK/BIK Proapoptotic Gene Alterations in Iranian Patients with Ataxia Telangiectasia, J Clin Immunol. 2010 Jan;30(1):132-7. Epub 2009 Nov 7.

 

۹۹٫ Abolhassan Shahzadeh Fazeli , Mohammad Hossein Sanati, Davood Nasrabadi, Alireza Pouya, Hossein Baharvand, Ghasem Hosseini Salekdeh, Central Nervous System Proteomics in Animal Model of Multiple Sclerosis Revealed Down-Regulation of Mithochondrial Proteins, Yakhteh Medical Journal,Vol 11, No 2, Summer 2009, Pages:236-243.

۹۸٫ Abdorrahim Sadeghi, Mohammad Hossein Sanati, Fatemeh Alasti, Morteza Hashemzadeh Chaleshtori, Saeid Mahmoudian, Mitra Ataei, Contribution of GJB2 mutations and Four common DFNB loci in autosomal recessive non-syndromic hearing impairment in Markazi and Qom provinces of Iran, Iranian Journal of Biotechnology (IJB), Vol 7, No 2 (2009), 108-111.

 

۹۷٫ Mojdeh Ghabaee, Asghar Bayati, Shahla Amri Saroukolaei, Mohamad Ali Sahraian, Mohammad Hosein Sanaati, Parisa Karimi, Massoud Houshmand, Homa Sadeghian, Leila Hashemi Chelavi, Analysis of HLA DR2&DQ6 (DRB1*1501, DQA1*0102, DQB1*0602) Haplotypes in Iranian Patients with Multiple Sclerosis, Cell Mol Neurobiol DOI 10.1007/s10571-008-9302-1.

۹۶. M. Jahanshahi, M.H.Sanati, S. Hajizadeh and Z. Babaei, Gelatin nanoparticle fabrication and optimization of the particle size, phys.stat.sol.(a)۲۰۵,No.12,2898 –۲۹۰۲ (۲۰۰۸)/DOI ۱۰.۱۰۰۲/pssa.200824329

۹۵٫ M. Jahanshahi, M. H. Sanati and Z. Babaei

Optimization of parameters for the fabrication of gelatin nanoparticles by the Taguchi robust design method

Journal of Applied Statistics, ۲۰۰۸, vol. 35, issue 12, pages 1345-1353.

۹۴٫ Mit Ghabaee M, Omranisikaroudi M, Amrisaroukolaei S, Meysamie A, Sahraian MA, Bayati A, Sanati MH, Houshman M, Sadeghian H, Vajihazaman K. Mitochondrial Mutation in Iranian Patients with Multiple Sclerosis, Correlation Between Haplogroups H, A and Clinical Manifestations. Cell Mol Neurobiol. 2008 Nov 14.

PMID: 19009343

 

۹۳٫ Solmaz Hajizadeh, Alexander E. Ivanov, Mohsen Jahanshahi, Mohamad H. Sanati, Natalia V. Zhuravleva, Lyubov I. Mikhalovska, Igor Yu. Galaev,

Glucose sensors with increased sensitivity based on composite gels containing immobilized boronic acid, Reactive & Functional Polymers 68 (2008)1625 –۱۶۳۵٫

 

 

۹۲٫ Jadali Z and Sanati MH

The autoimmune diseases manifested by production of autoantibodies: the autoantigens identified by random peptide library. Iran J Allergy Asthma Immunol. 2008 Sep; 7(3):115-31.

PMID: 18780947

 

۹۱٫

Allameh A, Maleklou N, Zargari M, Sanati MH. The influence of uric acid treatments on liver glutathione system prevent oxidative damages in experimental autoimmune encephalomyelitis mice. Neurosci Lett. 2008 Jul 4;439(1):111-5. Epub 2008 Apr 20.

PMID: 18501514

۹۰٫

Hilgert N, Alasti F, Dieltjens N, Pawlik B, Wollnik B, Uyguner O, Delmaghani S, Weil D, Petit C, Danis E, Yang T, Pandelia E, Petersen M, Goossens D, Favero J, Sanati M, Smith R, Van Camp G.

Mutation analysis of TMC1 identifies four new mutations and suggests an additional deafness gene at loci DFNA36 and DFNB7/11.

Clin Genet. 2008 Jun 26. [Epub ahead of print]

PMID: 18616530

۸۹٫

Banoei MM, Chaleshtori MH, Sanati MH, Shariati P, Houshmand M, Majidizadeh T, Soltani NJ, Golalipour M.

Variation of DAT1 VNTR alleles and genotypes among old ethnic groups in Mesopotamia to the Oxus region.

Hum Biol. 2008 Feb;80(1):73-81.

PMID: 18505046

 

۸۸٫

Alasti F, A. sadeghi, N.H. Sanati, M. farhadi, E. Stollar, T. Somers and G. Van Camp.

A Mutation in HOXA2 is responsible for autosomal recessive microtia in an Iranian family.

American Journal of Human Genetic, 2008, accepted for publication.

۸۷٫

Bayat B., S. Yazdian, A. Alavi, M. Chiani, F. Chitsazian, B. Khoramian, F. Suri, M. Narooie-Nejad, M. H. Sanati, and E. Elahi.

Contribution of MYCO and CYP1B1 mutations to JOAG, EJP, 2008, accepted for publication.

۸۶٫

Alasti F, Sanati MH, Behrouzifard AH, Sadeghi A, de Brouwer AP, Kremer H, Smith RJ, Van Camp G.

A novel TECTA mutation confirms the recognizable phenotype among autosomal recessive hearing impairment families.

Int J Pediatr Otorhinolaryngol. 2008 Feb;72(2):249-55.

PMID: 18022253

۸۵٫

Mehrizi AA, Zakeri S, Salmanian AH, Sanati MH, Djadid ND.

Plasmodium falciparum: Sequence analysis of the gene encoding the C-terminus region of the merozoite surface protein-1, a potential malaria vaccine antigen, in Iranian clinical isolates.

Exp Parasitol. 2008 Mar;118(3):378-85.

PMID: 18053992

۸۴٫

Bayat B, Houshmand M, Sanati MH, Moin M, Panahi MS, Aleyasin SA, Isaian A, Farhoodi A.

Use of D11S2179 and D11S1343 as markers for prenatal diagnosis of ataxia telangiectasia in Iranian patients.

Arch Med Res. 2007 Oct;38(7):803-5. Epub 2007 Jul 5.

PMID: 17845903 [PubMed – indexed for MEDLINE]

۸۳٫

Banoei MM, Chaleshtori MH, Sanati MH, Panahi MS, Majidizadeh T, Rostami M, Manshadi MD, Golalipour M.

Diversity and relationship between Iranian ethnic groups: human dopamine transporter gene (DAT1) VNTR genotyping.

Am J Hum Biol. 2007 Nov-Dec;19(6):821-6.

PMID: 17712789 [PubMed – indexed for MEDLINE]

۸۲٫

Chitsazian F, Tusi BK, Elahi E, Saroei HA, Sanati MH, Yazdani S, Pakravan M, Nilforooshan N, Eslami Y, Mehrjerdi MA, Zareei R, Jabbarvand M, Abdolahi A, Lasheyee AR, Etemadi A, Bayat B, Sadeghi M, Banoei MM, Ghafarzadeh B, Rohani MR, Rismanchian A, Thorstenson Y, Sarfarazi M.

CYP1B1 mutation profile of Iranian primary congenital glaucoma patients and associated haplotypes.

J Mol Diagn. 2007 Jul;9(3):382-93.

PMID: 17591938 [PubMed – indexed for MEDLINE]

۸۱٫

Golalipour M, Mahjoubi F, Sanati MH, Kamran A.

Gene dosage is not responsible for the upregulation of MRP1 gene expression in adult leukemia patients.

Arch Med Res. 2007 Apr;38(3):297-304. Erratum in: Arch Med Res. 2007 Nov;38(8):909.

PMID: 17350479 [PubMed – indexed for MEDLINE]

۸۰٫

Noori-Daloii MR, Hajebrahimi Z, Najafi L, Mesbah-Namin SA, Mowjoodi A, Mohammad Ganji S, Yekaninejad MS, Sanati MH.

A comprehensive study on the major mutations in glucose-6-phosphate dehydrogenase-deficient polymorphic variants identified in the coastal provinces of Caspian Sea in the north of Iran.

Clin Biochem. 2007 Jun;40(9-10):699-704. Epub 2007 Apr 6.

PMID: 17499234 [PubMed – indexed for MEDLINE]

۷۹٫

Sabouri A.A., H. Ghourchaei, M.H. Sanati, M.S. Atri, M. Rezaei-Tawiriani and G.H. Hakimelahi.

Binding properties and structural changes of human growth hormone upon interaction with cobalt ion, Journal of Thermal analysis and Calorimetry, Vol. 89 (2007) 3, 921-927.

۷۸٫

Zargari M, Allameh A, Sanati MH, Tiraihi T, Lavasani S, Emadyan O.

Relationship between the clinical scoring and demyelination in central nervous system with total antioxidant capacity of plasma during experimental autoimmune encephalomyelitis development in mice.

Neurosci Lett. 2007 Jan 22;412(1):24-8. Epub 2006 Dec 8.

PMID: 17157437 [PubMed – indexed for MEDLINE]

۷۷٫

Bairamijamal F., M.H. Sanati, M.M. Banoei, B. Bayat,

Genetic Polymorphism Analysis of NAD(P)H: quinine Oxidoreductase 1 in Different Iranian Ethnic Groups, Arjmand and D. Farhud, Current Science, Vol. 91, No. 8, 2006.

Houshmand M, M.H. Sanati, B Hooshiar Kashani, M Shafa Shariat Panahi, Y Eisaian, M. Moien, M Farhoudi.

Role of mitochondria in Iranian Ataxia-Telangiectasia: Investigation of mitochondrial deletions and Haplogroups, Iranian Journal of Biotechnology (IJB), Vol.4, No. 1, 2006, ۶۴-۶۸٫

۷۶٫

Elahi E, Khodadad A, Kupershmidt I, Ghasemi F, Alinasab B, Naghizadeh R, Eason RG, Amini M, Esmaili M, Esmaeili Dooki MR, Sanati MH, Davis RW, Ronaghi M, Thorstenson YR.

A haplotype framework for cystic fibrosis mutations in Iran.

J Mol Diagn. 2006 Feb;8(1):119-27.

PMID: 16436643 [PubMed – indexed for MEDLINE]

۷۵٫

Hassani-Kumleh H, Houshmand M, Panahi MS, Riazi GH, Sanati MH, Gharagozli K, Ghabaee M.

Mitochondrial D-loop variation in Persian multiple sclerosis patients: K and A haplogroups as a risk factor!!

Cell Mol Neurobiol. 2006 Mar;26(2):119-25. Epub 2006 May 6.

PMID: 16763779 [PubMed – indexed for MEDLINE]

۷۴٫

Kumleh HH, Riazi GH, Houshmand M, Sanati MH, Gharagozli K, Shafa M.

Complex I deficiency in Persian multiple sclerosis patients.

J Neurol Sci. 2006 Apr 15;243(1-2):65-9. Epub 2006 Jan 18.

PMID: 16413582 [PubMed – indexed for MEDLINE]

۷۳٫ Mosayebi G., Moazzeni S.M., Sanati M.H.

Effect of Sex on Susceptibility to Experimental Autoimmune Encephalomyelities Induced with MOG35-55 Peptide in C57BL/6 Mice, Medical Journal of Tabriz University of Medical Sciences, Vol. 27, No. 4, 2006.

۷۲٫

Mosayebi G, S.M. Moazzeni and M.H. Sanati,

Prevalence of Malignant Lesions in Single Cold Thyroid Nodules and Determination Accuracy of FNAB in These Single Cold Nodules, Medical Journal of Tabriz University of Medical Science, Vol. 28, No. 4, 2006, 95-100.

۷۱٫

Montazeri M, M. Houshmand, M. Shafa Shariat Panahi, F. Noohi, G. Nozar, M.H. Sanati, E.V. Zaklyazminskaya,

Investigation of Polymorphisms In non-coding Region of human Mitochondrial DNA in 31 Iranian Hypertrophic Cardiomyopathy (HCM) Patients. Iranian Journal of Biotechnology, 2006 July; Vol. 3, No. 3, 157-162.

۷۰٫

Mirsaeidi SM, Houshmand M, Tabarsi P, Banoei MM, Zargari L, Amiri M, Mansouri SD, Sanati MH, Masjedi MR.

Lack of association between interferon-gamma receptor-1 polymorphism and pulmonary TB in Iranian population sample.

J Infect. 2006 May;52(5):374-7. Epub 2005 Oct 17.

PMID: 16233916 [PubMed – indexed for MEDLINE]

۶۹٫

Noori-Dalooii M.R., Hejazi S.H., Yousefi A., Mohammad gangi S., Soltani S., Javadi K.R. and Sanati M.H.

Identification of Mutations in Glucose-6-Posphate Dehydrogenase (G6PD) Gene in Patients in Hormozgan Province of Iran, Journal of Science (I.R. of iran), 17(4):313-316, 2006.

۶۸٫

Noori-Daloii M.R., S. Soltanian, S. H. Mohammad Gangi, A. Yousefi, S. Hejazi, A. Bani-hashemi, S. Hitratfar, and M. Sanati,

Molecular Identification of the Most Prevalent Mutations of Glucose-6-Posphate Dehydrogenase (G6PD) Gene in Deficient Patients in Khorasan Province of Iran, Journal of Sciences (I.R. of Iran), 17(20): 103-106 (2006).

۶۷٫

Saboury AA, Atri MS, Sanati MH, Moosavi-Movahedi AA, Hakimelahi GH, Sadeghi M.

A thermodynamic study on the interaction between magnesium ion and human growth hormone.

                                                                                               Biopolymers. 2006 Feb 5;81(2):120-6.

PMID: 16208769 [PubMed – indexed for MEDLINE]

۶۶. Saboury A.A., M.S. Atri, M.H. Sanati, M. Sadeghi

Application of a Simple Calorimetric Data Analysis on the Binding Study of Calcium Ions by Human Growth Hormone, Journal of Thermal Analysis and Calorimetry, Vol. 83 (2006) 1, 175-179.

۶۵٫

Atri M.S, A.A Saboury, M. Rezaei-Tavirani, M.H. Sanati, A.A. Moosavi Movahedi, M. Sadeghi, H. Mansuri-Torshizi, K. Haghbeen,

Binding Properties and Conformational Change of Human Growth Hormone Upon Interaction with Fe, Thermochimica Acta, 438, 2005, 178-183.

۶۴٫

Esteghamat F, Noorinayer B, Sanati MH, Hekmatdoost A, Zafarghandi M, Shalmani HM, Agah M, Zali MR.

C77G mutation in protein tyrosine phosphatase CD45 gene and autoimmune hepatitis.

Hepatol Res. 2005 Jul;32(3):154-7. Epub 2005 Jun 15.

PMID: 15963758 [PubMed – in process]

۶۳٫

Hadavi V, D. Farhoud, M.H. Sanati, M. Houshmand, S.M. Navabi, M. Seyedian, M. Younesian

An Investigation of Human Apolipoprotein E Polymorphism in Multiple Sclerosis Patients of Iran,. Medical Journal of the Islamic Republic of Iran, Vol. 18, No 4, Feb. 2005, 297-301.

۶۲٫

Houshmand M, Sanati MH, Babrzadeh F, Ardalan A, Teimori M, Vakilian M, Akuchekian M, Farhud D, Lotfi J.

Population screening for association of mitochondrial haplogroups BM, J, K and M with multiple sclerosis: interrelation between haplogroup J and MS in Persian patients.

Mult Scler. 2005 Dec;11(6):728-30.

PMID: 16320736 [PubMed – indexed for MEDLINE]

۶۱٫

 Jadali Z, Esfahanian F, Eslami MB, Sanati MH.

Serum Antibodies against Hepatitis C Virus in Iranian Patients with Graves’ Disease

Iran J Allergy Asthma Immunol. 2005 Jun;4(2):91-4.

PMID: 17301428 [PubMed – in process]

۶۰٫

Jadali Z, Eslami MB, Sanati MH, Mansouri P, Mahmoudi M, Maghsoudi N, Esfahanian F.

Identification of peptides specific for antibodies in vitiligo using a phage library.

Clin Exp Dermatol. 2005 Nov;30(6):694-701.

PMID: 16197391 [PubMed – indexed for MEDLINE]

۵۹٫

Jadali Z, M.B. Eslami, M.H. Sanati, P. Mansouri, M. Mahmoudi, F.

Hepatitis C Virus Antibodies and Vitiligo Disease, Esfahanian, Iranian J Public Health, 2005, Vol. 34, No 1, pp.23-26.

۵۸٫

Moosavi MA, Yazdanparast R, Sanati MH, Nejad AS.

۳-Hydrogenkwadaphnin targets inosine 5′-monophosphate dehydrogenase and triggers post-G1 arrest apoptosis in human leukemia cell lines.

Int J Biochem Cell Biol. 2005 Nov;37(11):2366-79.

PMID: 16084123 [PubMed – indexed for MEDLINE]

۵۷٫

Manatunga V, H. Sanati, P. Tan and P.A. O’Brian

Maceration of Plant Tissue by Fungi is inhibited by Recombinant Antipectinase Antibodies, European Journal of Plant Pathology, (2005) 112: 211-220.

۵۶٫

Mosayebi G, S.M. Moazzeni and M.H. Sanati,

The Role of Spleen and Liver Dendritic Cells in Induction of TH1 and TH2 Response, Journal of Iran University of Medical Sciences, Vol. 12, No. 47, 2005, 135-143.

۵۵٫

Moosavi MA, Yazdanparast R, Sanati MH.

The cytotoxic and anti-proliferative effects of 3-hydrogenkwadaphnin in K562 and jurkat cells is reduced by guanosine.

J Biochem Mol Biol. 2005 Jul 31;38(4):391-8.

PMID: 16053705 [PubMed – indexed for MEDLINE]

۵۴٫

Moosavi MA, Yazdanparast R, Sanati MH, Nejad AS.

۳-Hydrogenkwadaphnin targets inosine 5′-monophosphate dehydrogenase and triggers post-G1 arrest apoptosis in human leukemia cell lines.

Int J Biochem Cell Biol. 2005 Nov;37(11):2366-79.

PMID: 16084123 [PubMed – indexed for MEDLINE]

۵۳٫ Noori-Daloii M.R, A. Yousefi, S. Mohammad Ganji, S.H. Hejazi, S. Soltanian, E. Sanei Moghadam, P. Bozorgzadeh and M.H. Sanati,

Molecular Identification of the Most Prevalent Mutation of Glucose-6-phosphate Dehydrogenase Gene in Deficient Patients in Sistan and Balochestan Province of Iran, Journal of Sceinces, Islamic Republic of Iran, 16(4):321-325, 2005.

۵۲٫

Saboury AA, Atri MS, Sanati MH, Moosavi-Movahedi AA, Haghbeen K.

Effects of calcium binding on the structure and stability of human growth hormone.

Int J Biol Macromol. 2005 Sep 28;36(5):305-9.

PMID: 16102809 [PubMed – indexed for MEDLINE]

۵۱٫ Saboury A.A, M. Kordbacheh, M.H. Sanati, F. Mizani, M. Shamsipur, M.B. Yakhchali, A.A. Moosavi Movahedi,

Thermodynamics of Binding Copper(II) Ion by Human Growth Hormone, Asian Journal of Chemistry, Vol. 17, No. 4, 2005, 2773-2782

۵۰٫

Sadeghi A, M.H. Sanati, F. Alasti, M. Hashemzadeh Chaleshtari,

Accesing Genetic and Environmental Factors of Hearin Loss in 354 Familis in Qom and Central Provices of Iran, Journal of Rehabilitation (English abstract), Vol. 6, No. 2, 2005, 7-10.

۴۹٫

Sadeghi A, M.H. Sanati, F. Alasti, M. Hashemzadeh Chleshtari, M. Ataei,

Mutation Analysis of Connexin 26 gene and del(GJB6-D13S1830) in Patients with Hereditary Deafness from two Provinces in Iran, Iranian journal of Biotechnology, Vol. 3, No. 4, 255-258, 2005.

۴۸٫ Tabandeh F, S.A. Shojaosadati, M. Khodabandeh and M.H. Sanati,

Optimization of Heat Induction Strategy in production of Human Growh Hormone During High Cell Density Culture of Escherichia coli, Vol. 3, No. 1, 24-30, 2005.

۴۷٫ Manatunga V, H. Sanati, P. Tan and P.A. O’Brien,

Macceration of Plant Tissue by Fungi is inhibited by Recombinant Antipectinase Antibody, European Journal of Plant Pathology, (2005) 112:211-220

۴۶٫ Yazdanparast R, Moosavi MA, Mahdavi M, Sanati MH.

۳-Hydrogenkwadaphnin from Dendrostellera lessertii induces differentiation and apoptosis in HL-60 cells.

Planta Med. 2005 Dec;71(12):1112-7.

PMID: 16395646 [PubMed – indexed for MEDLINE]

۴۵٫

Ahangari G, Ostadali MR, Rabani A, Rashidian J, Sanati MH, Zarindast MR.

Growth hormone antibodies formation in patients treated with recombinant human growth hormone.

Int J Immunopathol Pharmacol. 2004 Jan-Apr;17(1):33-8.

PMID: 15000864 [PubMed – indexed for MEDLINE]

۴۴٫ Ahangari G., Hassan Akrami, M.H. Sanati, and Ali Rabbani

Antibody production against E-coli polypeptide (ECP) by Dot blotting and ELIZA methods for ECP assay in recombinant drug and patients sera. Iranian Journal of Pediatrics. Vol. 13. 1, 2004.

۴۳٫ Biramijamal F., M.H. Sanati, G. Iravanloo, K. Shamimi and D. Farhud,

Detection of NAD(P): Quinone Oxidoreductase ۶۰۹ C > T Polymorphisem in Blood and Archival Human Tissues Using a Simple PCR Method, Iranian journal of Biotechnology Vol. 2.No.3.July 2004, ۲۰۳-۲۰۶

۴۲٫ Ghasemi F, A. Zomorodipour, S. Shojai, F. Ataei, M. Khodabandeh, M.H. Sanati

Using L-arabinose for Production of Human Growth Hormone in Escherichia coli, studying the Processing of gIII::hGH Precursor, Iranian Journal of Biotechnology, Vol. 2, No. 4, October 2004.

۴۱٫ Hadavi V, M.H. Sanati, D. Farhud, M. Houshmand, M. Hashemzadeh Chaleshtori, S.M. Nabavi, M. Younesian, M. Seyedian.

Association of Apolipoprotein E Polymorphism with Susceptibility to Multiple Sclerosis. Iranian Journal of Biotechnology, Vol. 2, No. 1, January 2004, 49-54.

۴۰٫

Houshmand M, Sharifpanah F, Tabasi A, Sanati MH, Vakilian M, Lavasani SH, Joughehdoust S.

Leber’s hereditary optic neuropathy: the spectrum of mitochondrial DNA mutations in Iranian patients.

Ann N Y Acad Sci. 2004 Apr;1011:345-9.

PMID: 15126312 [PubMed – indexed for MEDLINE]

۳۹٫ Houshmand M, M.H. Sanati, M. Vakilian, M. Akuchekian, F. Babrzadeh, M. Teimori, D. Farhud.

Investigation of the mitochondrial haplogroups M, BM, N, J, K and their frequencies in five regions in Iran. Iranian Journal of Biotechnology, Vol. 2, No. 1, January 2004; 44-48.

۳۸٫

Houshmand M, Sanati MH, Rashedi I, Sharifpanah F, Asghari E, Lotfi J.

Lack of association between Leber’s hereditary optic neuropathy primary point mutations and multiple sclerosis in Iran.

Eur Neurol. 2004;51(2):68-71. Epub 2003 Dec 10.

PMID: 14671420 [PubMed – indexed for MEDLINE]

۳۷٫

Alemohammad SA, DD Farhud, M Hooshmand, M Sanati, P Derakhshandeh-Peykar, SJ Imam, M Rahmani

Distribution of Mitochondrial DNA Intergenic COII/tRNALYS 9 bp

Deletion in Iranian Populations

Iranian J Publ Health, Vol.32, No.2, pp.1-5, 2003.

۳۶٫ Hormozian F, M. H.sanati, R.Ghiasvand, M.M Banoie.

Moulecular analysis of the (CAG)n repeat causing huntigton’s disease in 34 Iranian families,.Indian Journal of Human Genetic 2004 July-December, No.10.

۳۵٫ Manatunga V, M.H. Sanati, P. Tan and Philip A. O’ Brien.

Maceration of Plant Tissue by Fungi is inhibited by Recombinant Antipectinase Antibodies. European Journal of Plant Pathology. ۲۵ october ۲۰۰۴.

۳۴٫ Mosayyebi G., M.H. Sanati, Mohammad Moazzeni, and Mahnaz Aghayipour

Seperation, Phonotype determination and studying the performance of dandritic cells in of mice spleen using the flocytometer method, , Kosar Medical Journal, 9 (1), 11-19, 2004.

۳۳٫

Noori-Daloii MR, Najafi L, Mohammad Ganji S, Hajebrahimi Z, Sanati MH.

Molecular identification of mutations in G6PD gene in patients with favism in Iran.

J Physiol Biochem. 2004 Dec;60(4):273-7.

PMID: 15957246 [PubMed – indexed for MEDLINE]

۳۲٫

Sanati MH, Bayat B, Aleyasin A, Atashi Shirazi H, Isaian A, Farhoudi A, Moin M.

ATM Gene Mutations Detection in Iranian Ataxia-Telangiectasia Patients.

Iran J Allergy Asthma Immunol. 2004 Jun;3(2):59-63.

PMID: 17301393 [PubMed – in process]

۳۱٫ Sanati M. H., F. Alasti, H. Aleyasin, H. Mostafavi and P. Carnegie,

Expression and purification of recombinant Outer Surface Protein D (OspD) of Borrelia Burgdorferi, Archives of Razi J, 58, 2004, 19-27.

۳۰٫ Tabandeh F., S.A. Shojaosadat, A. Zomorodipour, M. Khodabandeh, M.H. Sanati and B. Yakhchali

Heat-Induced production of human growth hormone by high cell density cultivation of recombinant Escherichia coli.

Biotechnol Lett. 2004 Feb;26(3):245-50.

PMID: 15049371 [PubMed – indexed for MEDLINE].

۲۹٫ Tabandeh, F., Yakhchali, B., Shojaosadati, S.A., Khodabandeh, M., Sanati, M.H. “Growth kinetics and hGH production of a heat-inducible recombinant E.coli during batch fermentation”,  Iranian Journal of Science and Technology, 28(A1): 1-7, 2004.

۲۸٫ Zomorrodipour A, B. Yakhchali, M. Khodabandeh, A. Deezagi, S.M. Hosseini Mazinani, S. Valian Borujeni, M. Ahmadzadeh Raji, M. Rahimi, H. Ahmadi Daneshmand, M.H. Sanati,

The Over-Expression of Biologically Active Human growth Hormone in a T5-based System in Escherichia Coli, Studying Temperature Effect, Journal of Sciences (I.R. of Iran), 15(1): 27-32, 2004.

۲۷٫ Alasti F and M.H. Sanati,

Making an Experimental Animal Model for Multiple Sclerosis disease, Medical Journal of I.R. of Iran, 17(3): 245- 249, 2003.

۲۶٫ Arbabi M., F. Alasti, M.H. Sanati, S. Hosseini, A. Deldar, N. Maghsoodi

Cloning and Expression of Human Gamma-interferon cDNA in E.coli, Iranian Journal of Biotechnology, 1(2): 87-94, 2003.

۲۵٫ Dinparast Jadid N, M.H. Sanati, M. Zare and A. Hassanzehi,

rDNA-ITS2 Identification of Anopheles Pulcherrimus (Diphtera: Culicidae): Genetic Differences and Phylogenetic Relation with Other Iranian Vector and Its Implications for Malaria Control, Iranian Biomedical Journal, 7(1):1-6, 2003.

۲۴٫

Jadali1 Z, Eslami MB, Sanati MH, Mansoori P, Mahmoudi M, Maghsoodi N, Arbabi Ghahroudi M.

Identification of Hitherto Undefined B-Cell Epitopes by Antibodies in the Sera of Vitiligo Patients Using Phage-Display Peptide Library.

Iran J Allergy Asthma Immunol. 2003 Dec;2(4):197-201.

PMID: 17301381 [PubMed – as supplied by publisher]

۲۳٫

Khodabandeh M, B. Yakhchali, M.Rahimi, Z. Moghaddasi Jahromi, A. Zomorrodipour, A. deezagi, M.H. Sanati,

Purification of Large Quantities of Biologically Active Recombinant Human Growth Hormone, Iranian Journal of Biotechnology, 1(4):207-212,2003.

۲۲٫ Kiany J, A. Zomorodipour, M. Ahmadzadeh Raji, and M.H. Sanati,

Construction of Recombinant Plasmids for the Periplasmic Expression of Human Growth Hormone in Escherichia Coli under T7 and Lac Promoters, Journal of Sciences (I.R. of Iran), 14(4): 311-316, 2003.

۲۱٫ Noori-Daloii M.R., Z. Hajebrahimi, L. Najafi, S. Mohammad Ganji, M. Sadeghizadeh, and M.H. Sanati,

Molecular Identification of the Most Prevalent Mutations of Glucose-6- phosphate Dehydrogenase (G6PD) Gene in Deficient Patients in Gilan Province, Journal of Sciences (I.R. of Iran), 14(4): 327-331, 2003.

۲۰٫

Naz S, Alasti F, Mowjoodi A, Riazuddin S, Sanati MH, Friedman TB, Griffith AJ, Wilcox ER, Riazuddin S.

Distinctive audiometric profile associated with DFNB21 alleles of TECTA.

J Med Genet. 2003 May;40(5):360-3. No abstract available.

PMID: 12746400 [PubMed – indexed for MEDLINE]

۱۹٫ Rasti A., M. Moazeni and M.H. Sanati

Study of Humoral Immunity Borrelia in Sera and CSF of Multiple Sclerosis patients against Borellia antigens, Iranian Medical Journal of Yakhteh, Vol. 17, 35-41, 2003.

۱۸٫ Manijeh Rahmani, Seyed Mohammad Moazzeni and M.H. Sanati,

Studying lymphocyte Reaction in Multiple Sclerosis patients, Shahed University Journal of Daneshwar, 2003.

۱۷٫ Sanati M.H., C. Stanyon, D. Mehmet, F. Alasti and P. R. Carnegie,

Improved procedure for Screening Expression Libraries for Novel Autoantigens, Iranian Journal of Biotechnology, 1(1): 31-35, 2003.

۱۶٫ Tafreshi A.P., and M.H. Sanati

An In vivo Assay for Biological Activity of Synthesized Recombinant Human Growth Hormone, Arch. Razi Ins., 56, 2003, 103-108.

۱۵٫ Tabandeh F, S.A. Shojaosadati, B. Yakhchali, M. Khodabandeh and M.H. Sanati,

Evaluation of Heat Induction Strategy for Recombinant Human Growth Hormone Expression in Fed-Batch Fermentation,

Iranian Journal of Biotechnology, Vol. 3, No. 1, 2003, 24-30.

 ۱۴٫ Hossein Ale-Yasin, Ali Sarai, Farshid Alaeddini, Elaheh Ansarian, Jamshid Lotfi, Mohammad Hossein Sanati

Multiple Sclerosis: A study of 318 Cases, Archives of Iranian Medicine, Vol.5, No.1, 24-27, 2002.

۱۳٫ Mesbah-Namin SA, Sanati MH, Mowjoodi A, Mason PJ, Vulliamy TJ, Noori-Daloii MR.

Three major glucose-6-phosphate dehydrogenase-deficient polymorphic variants identified in Mazandaran state of Iran.

Br J Haematol. 2002 Jun;117(3):763-4.

PMID: 12028056 [PubMed – indexed for MEDLINE]

۱۲٫ Nouraei M. and M.H. Sanati,

Guideline Planning for Biotechnology Research, Journal for Research Programing in Higher Education, Vol. 3, 211-221, 2002.

۱۱.  Sanati M.H., P.R. Carnegie

Antibody to Mitochondrial complex-I in some patients with Multiple Sclerosis., Medical Journal of I. R. of IRAN, 15(4): 203-207, 2002.

۱۰. Sabouri A.A., S. Saeidian, Mohammad Hossein Sanati, A.A. Moosavi-Movahedi and F. Alasti,

Thermodinamic Studies of Myelin Basic Protein upon Interaction with zinc, Journal of the Chineese chemical Society, 48, 827-831, 2001.

۹. Alasti F. and M.H. Sanati

The importance of transgenic living creatures in biotechnology, J of Sharif University, Paper in Farsi with English Abstract, Vol. 18, 23-29, 2000.

۸٫ Mesbah Namin S.A., M.H. Sanati, A. Mowjoodi and M.R. Noori Daloii.

Spread of the Glucose-6-Phosphate Dehydrogenase variant (G6PD-Mediteranian) in one of the coastal Provinces of Caspian Sea in IRAN. Journal of Sciences (I.R. of IRAN), ۱۱ (۴): ۲۸۵-۲۸۸, ۲۰۰۰٫

 

۷٫ Sanati M.H. and P.R. Carnegie

Cloning and Sequencing of a Mitochondrial Autoantigen with Immunoglobulin G from Patients with Multiple Sclerosis. Journal of Sciences (I.R. Of Iran), 11(3): 181-186, 2000.

۶. M.H. Sanati, Hossein Ale Yassin,

Interoduction of the International Biosafety Protocol, Journal of the Iranian Biotechnology Commision, Vol. 2, 105-110, 1999.

۵. M.H. Sanati

Recombinant Human Growth Hormone , Journal of the Iranian Biotechnology Commision, Vol. 2, 58-63, 1999.

۴٫ Hossein Ale Yassin, M.H. Sanati

Human Genome Project (hopes and fears), Journal of the Iranian Biotechnology Commision, Vol. 1(2), 1998.

۳٫ Hossein Ale Yassin, M.H. Sanati

Human Genome Project (concepts and basics), Hossein Ale Yassin, M.H. ۷۷. Human Genome Project (concepts and basics), Journal of the Iranian Biotechnology Commision, 1(3), 25-30, 1988.

۲٫ M.H. Sanati,

Introduction of the “International Biotechnology and Genetic Engineering Research Center (ICGEB)”, Journal of the Iranian Biotechnology Commision, Vol. 1, 38-43, 1998.

۱٫  M.H. Sanati, Bagher Yakhchali

Introduction of the National Research Center for Genetic Engineering and Biotechnology (NRCGEB), Journal of the Iranian Biotechnology Commision, Vol. 1(2), 35-39, 1998.

 

Patent:

 

۱٫ M.H. Sanati and P.R. Carnegie,

A novel autoantigen in multiple Sclerosis, Patent, March 1995, PCT/AU96/00166, Murdoch university, Western Australia.

 

۲٫      M.H. Sanati, M. Jahanshahi and Z. Babaei.

 Production of gelatin nanoparticles for drug delivery to the target tissues, 43062, 23 Sep 2007. Organization for submitting the official documents of the Intelectual Property Right, Islamic Republic of Iran.

 

۲٫      M.H. Sanati

Haplotype markers for diagnosis of Ataxia Telangictasia, 29656, May 2004, Organization for submitting the official documents of the Intelectual Property Right, Islamic Republic of Iran.

 

Projects:

 

 a. As Principal investigator:

۱-    Preparation of the National Strategy for Biotechnology Development. In this 3 year project, I had the leadership of more than 200 specialists in 8 research groups. The result of this project was the finalization of the National Strategic Plan for Biotechnology development in Iran, which was ratified by the Iranian government in 2005.

۲-    Research project titled: Study of the presence of antibodies against Borrelia proteins in Sera and CSF of Multiple Sclerosis patients and determinig the immunological activity of these proteins in animal models.

۳-    Cloning auto-antigenes in Multiple Sclerosis.

۴-    Production of Recombinant Human Growth Hormone (phase 2 and 3).

۵-     Studying the Mutation of Ataxia Telangictasia in Iranian patients.

۶-    Studying the genetic factors of Multiple Sclerosis.

۷-    Preparation of Encyclopaedia in Biotechnology and Genetics.

۸-    Determinig the normal level of biochemical factors in infants’ sera.

۹-    Genetic study of hearing impairments in Iranian patients.

۱۰- Cloning and Expression of Human Gamma Interferon in Bacteria.

۱۱- Genetic study of Visual Impairment (Congenital Glaucoma). This is a collaboration research project granted by WHO-COMSTECH.

 b. As Collaborating Investigator:

۱-    The National project for Capacity Building in Biosafety. This project was performed in the frameworks and as part of the Cartagena Protocol on Biosafety, in national level in the Environmental Department of Iran and my responsibilities in this project included holding educational workshops and preparing the overall strategy of the project and prepating final report.

۲-    Studying the mutations of the G6PD gene in patients with favism in the Northern Provinces of Iran.

۳-    Production of Recombinant Gama Interferon. A Research Project Granted by NIGEB.

۴-    Production of Novel Hormone (GnRH) for Induction of Spawning in Carp, Trout, and Sturgeons, a Research Project Granted by NIGEB.

Various Executive and Scientific Activities:

۱-    Chairman and Editor-in-Chief of the Iranian Journal of Biotechnology (IJB) since 2003 to 2007.

۲-    Member of the Khwarazmi Scientific Award judgment committee, since 2001 till now.

۳-    Member of the evaluation committee of the field of Genetics in the Iranian Ministry of Health since 2000 to 2003.

۴-    Secretary of the National Biotechnology Committee (Iranian Ministry of Science, Research and Technology) since 2000 to 2005.

۵-    Secretary of the National Biosafety Committee (Iranian Ministry of Science, Research and Technology) from 1999 to 2005.

۶-    Secretary of the first International Bioethics Congress held from 26th to 28th March 2005, Tehran, Iran.

۷-    Secretary of the 1st National Biotechnology Congress, Tarbiat Modarres University, Tehran, Iran in 1999.

۸-    Member of the Genetic Committee, National welfare Organization, Tehran, Iran, 2002 – ۲۰۰۴٫

۹-    Chairman of the Iranian Biotechnology Society, 2000 – ۲۰۰۶٫

۱۰-  Member of the Editorial Board of the Scientific Journal named: Archive of Razi, since 2000 until now.

۱۱- Member of the Editorial Board, Iranian Journal of Immunology, Asthma and Allergy, year 2003 until now.

۱۲-  Member of the “Federation of European Biotechnology (FEB)”, since year 2002 until now.

۱۳- Member of the Iranian Genetic Society, year 2000 until now.

۱۴- Member of the “Iranian Ethics Society for Science and Technology” as well as the member of Founder and management Committee, since year 2005.

۱۵- Governor for International Center for Biotechnology and genetic engineering (ICGEB), Trieste, Italy, 1999-2005.

۱۶- Member of the Biotechnologi Information of Asia (BINASIA), as a national representative for Iran, 2003-2006, Coordinated by KRIBB and APCTT.

۱۷- Member of the Iranian Delegation Team at the Negotiation Meetinge for International Biosafety Protocol, UNEP/CBD:

–                 ۱۴ -۱۹ and 22-23 Feb. 1999, Sixth Ordinary Meeting of the Ope-Ended Ad Hoc working Group on Biosafety Protocol, and the Extraordinary Meeting of the Conference of the Parties to the Convesion on Biologicad Diversity, Cartagena, Colombia.

–                 ۲۹ Jan. 2000, Organizational Meeting of the Intergovenmental Committee for the Cartagena Protocol on Biosafety, Montreal, Canada.

–                 ۱۱-۱۵ Dec. ۲۰۰۰, first Meeting of the Intergovenmental Committee for the Cartagena Protocol on biosafety, Montpellier, France.

–                 ۲۲-۲۶ Apr. 2002, Third Meeting of the Intergovernmental Committee for the Cartagena Protocol on biosafety, The Hague, Netherland.

–                 ۲۳-۲۷ Feb. 2004, First Meeting of the Conference of the Parties Serving as the Meeting of the Parties for Cartagena Protocol on Biosafety, Kuala Lumpur, Malaysia.

Awards:

۱٫     Selected manager according the criteria identified by Ministry of Science, Research and Technology in 2001 and receiving the award from Iranian President Seyed Mohammad Khatami.

۲٫     Award for top research project in biotechnology “Production of Recombinant Human Growth Hormone”, 2000, Tehran, Iran.

۳٫     Award for best oral paper presentation in the general biological science conference in 1994 in Perth, Western Australia.

۴٫     Award for top paper presented in the 47th meeting of the heads of universities and research centers of Iran in 2002.

۵٫     Award from Iranian President Seyed Mohammad Khatami for Organizing the first International Bioethics Congress in Iran and paper Presentation in this Field.

۶٫     Award received from Iranian Minister of Science, Research and Technology, for Carrying out the “National Strategic Plan for Development of Biotechnology across the Country” Project and Success in Preparation of the Documents which was ratified by the Government.

 

Thesis: As Supervisor

۱٫ Study of association between MRP1 gene and multidrug resistance in leukemic patients. Theisi by Masoud Golalipour for Phd degree in molecular genetic, Tarbiat Modarres University, Tehran, Iran, 2007.

۲٫ Linkage analysis of some autosomal recessive deafness loci and detection of new mutation in some population of Iran. Thesis by Abdorrahim Sadeghi for PhD degree in molecular genetic, Tarbiat Modarres University, Tehran, Iran, 2006.

۳٫ Investigation of relationship between NDUFS1 gene with Multiple Sclerosis. Theisi for MsC degree in molecular genetic by Zohre Baratieh, Khatam University, Tehran, Iran, 2007.

۴٫ Isolation and Characterization of Reacting Peptides with antibody Isolated from Vitiligo Patients Sera, Thesis by Z. Jadali for PhD Degree in Medical immunology, Tehran University of Medical Sciences, Tehran, Iran, 2006.

۵٫ Linkage analysis of DNFB3 and DNFB21 Loci in Non Syndromic Autosomal Recessive Hearing Loss in Iranian Population, Thesis By M.H. Behroozi-fard for MS.c Degree in Cell and molecular Biology, Khatam University, Tehran, Iran, 2005.

۶٫ Investigation of Four SNP Markers as well as a YAP Marker of Y Chromosome in Three Iranian Ethnic group (Fars, Tork and Kord). Thesis By R. Abbasi-Zamharir for MS.c Degree in Cell and molecular Biology, Khatam University, Tehran, Iran, 2004.

۷٫ Screening of 12-mer Random Peptide Phage Display Library on Leprosy Patient Sera, Malek Ashtar University, Thesis by M.R. Khatami for MS.c Degree in Molecular Biotechnology, Tehran, Iran, 2003.

۸٫ Mutation and Chromosomal Haplotype Analysis in ATM Gene in Iranian Ataxia Telagictasia Patients, Thesis By S. Lotfipanah for MS.c Degree in Cell and molecular Biology, Khatam University, Tehran, Iran, 2004.

۹٫ Study of C77G Mutation in Protein Tyrosin Phosphatase Gene CD45 in Hepatitis Autoimmune Patients, Thesis By F. Sadat Esteghmat Hanzaei for MS.c Degree in Cell and Molecular Biology, Khatam University, Tehran, Iran, 2004.

۱۰٫ Mutation Analysis in Iranian Ataxia Telangictasia Patients, Thesis By H. Atashi Shirazi for MS.c Degree in Cell and Molecular Biology, Khatam University, Tehran, Iran, 2002.

۱۱٫ Analysis of Tri-Nucleotide Repeats (CAG) in Iranian Families Suffering from Huntington Disease, Thesis By F. Hormozian for MS.c Degree in Human Genetics, Azad University, Tehran, Iran, 2000.

۱۲٫ Study of the Relationship between Mitochondrial Haplogroup M and Multiple Sclerosis diseases, Thesis by M. Timouri for MS.c Degree in Cell and Molecular Biology, Research and Science Unit, Azad University, Tehran, Iran, 2003.

۱۳٫ Detection of Polymorphism In the Apo-E Region and the Association with Progression of Multiple Sclerosis, Thesis By V. Hadavi for MS.c Degree in Human Genetic, Faculty of Health, Tehran Medical Science University, Tehran, Iran, 2003.

۱۴٫ Investigation of mutation in Exon 3 of Gene CYP1B1 in 60 Iranian Family Suffering from Glaucoma. Thesis By F. Chitsazan for MS.c Degree in Cell and Molecular Biology, Faculty of Science, Tehran University, Tehran, Iran, 2005.

۱۵٫ Proteomics Profiling of the Central Nervous System in Murine Exprimental Autoimmune Encephalomylities befor and after treatment with Neural precursor Cells Drived from Mouse Emberionic Stem Cell, Thesis by S.A. Shahzadeh Fazeli for PhD Degree in Molecular Genetic, National Institute for Genetic Engineering and Biotechnology, Teharn, Iran, 2010.

۱۶٫ The role of BAX, BAK and BIK gene mutations in ataxia telangictasia, and AT with lymphoma or leukemia, and in the ATM carrier and reaction of these genes in cancers of lymphoma and leukemia, Thesis by Anna Isaian for PhD Degree in Molecular Genetic, National Institute for Genetic Engineering and Biotechnology, Teharn, Iran, 2010.

۱۷٫ Investigation of the molecular techniques for the diagnosis of thalasemia and identifying the method of choice, Thesis by Fatemeh Kashani Motlagh for M.Sc Degree in Biology/Biochemistry, Payam Noor University, Teharn, Iran, 2010.

۱۸٫ Investigation of the role of maternal KIR and paternal HLA-C genotype in recurrent miscarriage, Thesis by Mona Khosravi, Azarbaijan University of Tarbiat Moalem, for M.Sc Degree in Cell and Molecular Biology, Azarbaijan, Iran, 2010.

۱۹٫ Study of relationship between endothelial nitric oxide synthase polymorphism & recurrent miscarriage, Thesis by Fatemeh Abbasi, Azrbaijan University of Tarbiat Moalem, for M.Sc Degree in Cell and Molecular Biology, Azarbaijan, Iran, 2010.

 ۲۰٫ Study of association between multiple sclerosis and the polymorphisem in ILII alpha receptor gene, Thesis by Mostafa Ali for M.Sc Degree in Cell and Molecular Biology, Azad University, Tehran, Iran, 2009.

۲۱٫ Study of association between multiple sclerosis and the polymorphisem in mitochondrial polymerase gama gene, Thesis by Hossein Soltanzadeh for M.Sc Degree in Cell and Molecular Biology, Azad University, Tehran, Iran, 2008.

۲۲٫ Study of the expression patern of splice variants of N-type voltage-dependent calcium channel alpha 1 subunit in rat hyppocampas and lumber spinal cord, Thesis by Sareh Asadi for M.Sc Degree in Cell and Molecular Biology, Tarbiat Modarres University, Tehran, Iran, 2008.

۲۳٫ Study of hot spot mutations in Iranian patients suffered from cystic fibrosis, Thesis by Mahnaz Amiri for M.Sc Degree in Cell and Molecular Biology, Khatam University, Tehran, Iran, 2003.

Thesis: as Co- Supervisor

۱٫ Point Mutations Analysis in LHON Patients with Nerve degeneration. Thesis By F Sharifpanah for MS.c Degree in Human Genetic, Research and Science Unit, Azad university, Tehran, Iran, 2001.

۲٫ Isolation and identification of Sulfide/Sulfoxide Monooxygenase Gene from Rhodococcus FMF, Thesis by M. Kazemi for MS.c Degree in Genetic, Research and Science Unit, Azad University, Tehran, Iran, 2002.

۳٫ Biochemical Diagnosis and Determination of Q188R, K285N, L195P, X380R and Q169K Mutations in Galactosemic Patients, Thesis By N. Naghibzadeh for MS.c Degree in Human Genetic, Research and Science Unit, Azad university, Tehran, Iran, 2003.

۴٫ Study of Interaction between Myelin Basic Protein (MBP) and Zn and Cu Ions, Thesis By S Saeidi for MS.c Degree in Biochemistry, Institute for Biophysics and Biochemistry, Tehran University, Tehran, Iran, 2000.

۵٫ Study of Y Chromosome Microdeletions in Iranian Infertile Men, Thesis By S Ghavam-Poor for MS.c Degree in Cell and molecular Biology, Faculty of sciences, Tehran University, Tehran, Iran, 2003.

۶٫ An Investigation of Chromosomal Abnormalities and physiological Deficiencies in Mentally Retard Boys, Thesis By B. Bayat for MS.c Degree in Biology, Faculty of sciences, Shahid Baheshti University, Tehran, Iran, 1998.

۷٫ Study of G6PD Gene Mutations in Patients from Golestan Province of Iran, Thesis By L. Najafi for MS.c Degree in Genetic, Faculty of Basic Sciences, Tarbiat Modarres University, Tehran, Iran, 2003.

۸٫ Study of Mitochondrial Haplogroup J, M, BM and N in Iranian Families and its relation to LHON Disease, Thesis by M. Vakilian for MS.c Degree in Human Genetic, Faculty of Health, Tehran Medical Science University, Tehran, Iran, 2003.

۹٫ Identification of Molecular Mutations of G6PD Gene in Deficient Patients in State of Mazandaran, Thesis by A. Mesbah-Namin for PhD Degree in Clinical Biochemistry, Faculty of Basic Medical sciences, Tehran, Iran, 2001.

۹٫ Study of G6PD Gene Mutations in Patients from Gilan Province of Iran, Thesis By Z. Haj-Ebrahimi for MS.c Degree in Genetic, Faculty of Basic Sciences, Tarbiat Modarres University, Tehran, Iran, 2003.

۱۰٫ Analysis of Four Locus (DaT1, D1S80, D17S5 and ApoB) Markers In three Ethnic Group Azeri Fars and Kord. Thesis by N. Jahangir Soltani for MS.c Degree in Cell and Molecular Biology, Research and Science Unit, Azad University, Tehran, Iran, 2005.

۱۱٫ Study of Four Microstelite Markers (DYS19, DYS388, DYS390 and DYS391) in three Province of Iran Fars, Azarbayejan Sharghi and Kurdistan, Thesis by R. Mirzazadeh Nafe for MS.c Degree in Cell and Molecular Biology, Research and Science Unit, Azad University, Tehran, Iran, 2005.

۱۲٫ Study of Four Markers (D19S20, ApoB, D17S5 and D1S80) in two Province of Iran Lorestan and Sistan-Baloochestan, Thesis by A Mahianeh for MS.c Degree in Cell and Molecular Biology, Research and Science Unit, Azad University, Tehran, Iran, 2005.

۱۳٫ Study of Four Y-STR Markers (DYS392, DYS393, DYS391 and DYS389II) In three Ethnic Group in Iran, Azari, Fars and Kord, Thesis By M. Marvi for MS.c Degree in Cell and Molecular Biology, Research and Science Unit, Azad University, Tehran, Iran, 2005.

۱۴٫ Study of Four Polymorphic Allele in Y-Chromosome In three Ethnic Group in Iran, Azari, Fars and Kord, Thesis By M. Amidi for MSc Degree in Cell and Molecular Biology, Research and Science Unit, Azad University, Tehran, Iran, 2005.

۱۵٫ Study of Four Mutations W1282X, G551D, G542X, DeltaF508 and N1303K in Iranian Patients affected to Cystic Fibrosis, Thesis by M. JalaliRad for MS.c Degree in Cell and Molecular Biology, Faculty of Science, Gilan University, Iran, 2005.

۱۶٫ Production and optimization of gelatin nanoparticle for drug delivery, thesis By Zahra Babaei for MS.c Degree in chemical engineering, Noshirvani university, Babol, Mazandaran, Iran, 2005.

 ۱۷٫ Linkage analysis of three loci in non syndromic autosomal recessive deafness patients from Qom and Markazi provinces of Iran, thesis By M. Sadat Taghavi for MS.c Degree in Cell and Molecular Biology, Azad university, Tehran, Iran, 2008.

۱۸٫ Cloning, expression and evaluation of plasmodium vivax and P. Falciparum region of Merozoite Surface Protein 1 in animal model, thesis By Akram Abouie Mehrizi for PhD Degree in Molecular Genetics, National Institute for Genetic Engineering and Biotechnology, Tehran, Iran, 2010.

 

۱۹٫ Determination of frequency mutations in the first half of exon 2 of CYP1B1 gene among 60 iranian patients afflicted with Primary Congenital Glaucoma, thesis By Btsabeh Khoramian Tusi for M.Sc Degree in Cell and Molecular Biology, Tehran University, Tehran, Iran, 2006.

 

Publications

 a. Published books written in Farsi language Except for No. 7 which is in both Farsi and English and No. 8 which is in English.

۱Genetic and You, General Information in Genetic, M.H. Sanati, Ali Reza Mowjoodi and Sakineh Abbasi, 1998.

۲٫     Genetic Engineering, Technology for manipulation of Living Organisems, M.H. Sanati, M. Khazab, C. Azeempoor, In Farsi, 2000.

۳٫     International Biosafety Protocol, Translation of Cartagena Protocol to Farsi, M.H. Sanati and Colleagues, 2001.

۴٫     Biotecnology, a solution to solve mankind problems during the 21th century, M.H. Snati and N. Ismailzadeh, 2001.

۵٫     Biosafety Guidlines, In Farsi, M.H. Sanati and Colleagues, 2001.

۶٫     Bioethics and Biotechnology, M.H. Sanati and Colleagues, 2002.

۷٫     The Tehran Statement and the Final Report of the International Congress of Bioethics in Iran, A book which has been written in cooperation and financial support by UNESCO In both English and Farsi Language, M.H. Sanati and Colleagues, 2006.

۸٫     Understanding Bioethics, M.H. Sanati and Colleagues, 2005.

۹٫     Editor in Cief and co-authors for the “Encyclopedia of Biotechnology and Genetics, 2009.

 

 

 

b.  Selected Abstract presented in different scientific congress:

 

۱٫ Haplotype Analysis of Related ATM Markers Facilitate Prenatal Diagnosis in Iranian Ataxia Telangictasia Patients. Bayat B, Sanati M, Alyasin A, Moein M, Farhoodi, Eesaian A, Human Genome Diversity in Islamic Countries Seminar, 7-8 May 2002 Tehran, Iran.

۲٫ Investigation of mtDNA Haplogroups and Disease (Report from Iran)

Houshmand M., Sharifpanah F, Alemohamad A, Rahmani M, Joughehdost S,Babrzadeh F., Vakilian M, Sanati MH, Human Genome Diversity in Islamic Countries, 7-8 May, 2002, Tehran, IRAN

۳٫ Some Molecular Genetic Aspects of Hearing Loss in Iranian Population.

F. Alasti, M. H. Sanati, Ed. Wicox, Salehi Tabar, A. Mojoodi and T.B. Friedman, Human Genome Diversity In Islamic Countries, Seminar 7-8 May 2002, Tehran,Iran.

۴٫ Absence of Mitochondrial DNA Intergenic COII/ t RNA Lys 9 bp Deletion within a sample of Iranian Populatons, Alemohamad S., Rahmani M, Houshmand M., Farhoud D, S., Sanati M.H, Human Genome Diversity In Islamic Countries Seminar, 7-8 May 2002, Tehran, Iran.

۵٫ Introduction of Patients Cell Bank in National Research Center for Genetic Engineering and Biotechnology, M. M. Banoei, F. Hormozian, F. Mirzajaani, M. Houshmand, M.H. Sanati, Human Genome Diversity In Islamic Countries, 7-8 May 2002, Tehran, Iran.

۶٫.Relation Between LHON primary Point Mutations and MS, Sanati M.H., Sharifpanah F., Houshmand M., Rashedi F, Asghari R.E., Lotfi J, Human Genome Diversity In Islamic Countries Seminar, 7-8 May 2002, Tehran, Iran.

۷٫ Molecular Analysis of Iranian Patients with Huntington’s Disease, F. Hormozian , M. Houshmand, R. Ghiasvand, M.H Sanati, Human Genome Diversity in Islamic Countries, 7-8 May 2002, Tehran, Iran.

۸٫ Genetic Counseling Report (one Year Experiences( , Joughedoust S., Shafeghati Y., Molavi M., Sobouti S., Babamohamadi G.H.R. ,Zolfaghari N., Houshmand M. and Sanati M.H., Human Genome Diversity In Islamic Countries, 7-8 May 2002, Tehran, Iran.

۹٫ Detection of Mitochondrial Mutation in Iranian Deaf Families., Salehi Tabar R., Sanati M.H., Mowjoodi A., Elahi E. and Houshmand M., Human Genome Diversity In Islamic Countries, 7-8 May 2002, Tehran, Iran.

۱۰٫ Distribution of 9bp Deletion between the Lys tRNA and COII region of mtDNA in Iranian populations., Allemohammad SA, Rahmani M., Houshmand S.M., Sanati M.H., Farhud D.,Euromit ۵, Venice, Italy, 19-23 sep. 2001., Mitochondrion (The official Journal of the Mitochondrial Research Society), Vol.1, Suppl.1 sep. 2001, ISN 1567-7249

۱۱٫ Detection of Mitochondrial Mutation in Iranian Deaf Family., Salehi Tabar R., Sanati M.H., Mowjoodi A, Sokhansanj A., Elahi E., HoushmandM., Euromit 5, Venice , Italy, 19-23 Sep. 2001.,Mitochondrion (the official Journal of the Mitochondrial Research Society), Vol. 1, Suppl. 1, Sep.2001, ISSN 1567-7249.

۱۲٫ Relationship between LHON primary point Mutations and MS ., Sanati M.H., Sharifpanah F., Houshmand M. Euromit 5, Venice, Italy, 19-23 sep.2001. Mitochondrion (The official Journal of The Mitochondrial Research Society), vol.1,SUPPL.1, Sep. 2001, ISSN 1567-7249.

۱۳٫  Investigations of Proliferation Response of Multiple Sclerosis patients’ Lymphocytes against Borrelia Antigens., Rahmani M., Moazzeni S.M., Sanati M.H, Euromit 5, Venice, Italy, 19-23 sep.2001. Mitochondrion (the official Journal of the Mitochondrial Research Society),Vol. 1, SUPPL. 1, Sep. 2001, ISSN 1567-7249.

۱۴٫ Three Major G6PD-Deficient Polymorphic Variants Identified in the Mazandaran State of Iran., S.A. Mesbah Namin, M.H. Sanati, A. Mowjoodi, T.J. Voliamy and M.R.Noori-Daloii, 9th APCCB, 28th Annual Conferece of ACBI, 9-14 March 2002, NewDelhi, India

۱۵٫ Haplotype Analysis of related ATM Markers Facilite prenatal Diagnosis in Iranian Ataxia Telangiectasia Patients., B. Bayat, M.H. Sanati, A. Aleyasin, A. Farhoudi, M. Moin, A. Isaian., EuropeanHuman Genetics Conferece , 25-28 May 2002, Strasbourg, France., European Journal of Human Genetics, Vol. 10, Suppl. 1. May 2002.

         ۱۶- Introducing of Iranian Patients Cell Bank in the National Research center

         for Genetic Engineering and Biotechnology (NRCGEB(, M.M. Banoei,

         F.Hourmozian, M. Houshmand, M.H. Sanati, European Human Genetics

         Conferece, 25-28 May 2002 Strasbourg, France. European Journal of Human

         Genetics, Vol.10, Suppl.1, May 2002,

۱۷٫ Investigation of LHON Primary point Mutations in Iranian MS Patients.

H. Houshmand, E. Sharifpanah, M. Sanati, A. Tabasi, Y. shafeghati.

European Journal of Human Genetics, Vol. 10, Suppl. 1, May 2002.

۲۵-۲۹ May 2002 , strasbourg, France.

۱۸٫  Molecular Analysis of Iranian Patients with Huntington’s Disease.

F. Hormozian, M. Houshmand, R. Ghiasvand, M. Sanati, 10th InternationalCongress of Human Genetics, May 15-19, 2001, Vienna, Austria.

European Journal of Human Genetics vol. 9, Suppl. 1, May 2001.

۱۹٫  First Report on Molecular Identification of Anopheles Pulcherrimus by using rDNAITS2 Region , Navid Dinparast jadid, S. Zeinali, M.H. Sanati, M. Zare, A. Hassan zehi

۲۰٫ Identification of p53 genotype among Iranian Ataxiatelangiectasia (A-T) Patients, Behnaz Bayat, Firouzeh Biramijamal, Mohammad Hossein Sanati, Mohammad mehdi Banoei

۲۱٫ Studying the Production of Human Growth Hormone under T7/LacRegulatory System in Escherichia Coli., Alireza Zomorodipour , Abdolkhalegh Deezaji, & Mohammad Hossein Sanati , Medical Biotechnology Congress, 20-25 Oct. 2002, Japan.

       ۲۴- Progress in Multiple Sclerosis Research, 16-19 Sep 1995 Canberra,

       Australia. the FAOBMB congress, 24-29 Sep 1995, Sydney, Australia.

۲۵٫ Combined Biological Science Meeting, 4th Aug 1995, University of WesternAustralia, Perth, Australia.

۲۶٫ International Symposia on Myelin and Myelin Forming Cells, 1995, Okazaki, Japan.

۲۷٫ ‍Progress in Multiple Sclerosis Research, 1994, Canberra, Australia.   ۵۳٫ ۱۶th International Congress of Biochemistry and Molecular Biology, New Dehli, 1994.

۲۸٫ Second Asian Pacific Society for Neurochemistry (APSN) Meeting, Heydrabad, India, 1994.

۲۹٫ Combined Biological Science Meeting, 19th Aug 1995, University of Western Australia, Perth.

۳۰٫ Gordon Conference on Myelin, 13-18 Mar 1994, California, USA.

۳۱٫ “Determination of normal level of biochemical factors in infants sera in south of Iran”, Sanati M.H., Biochemistry Meeting, Tarbiat Modarres University, Tehran, Iran.

۳۲٫ “Producation of antibody againstthe organophosphorous compounds”, M. H. Sanati, Z. M. Hassan and M.Taghikhani, 9th Iranian Congress of Physiology and Pharmacology, University of Shahid Beheshti, Tehran, Iran, 1989.

۳۳٫ “Hapten-Protein Conjugation”, Sanati M.H. and Hassan Z. M., First Iranian congress of immunology and allergy in Tehran University, Tehran, Iran, 1988.

۳۴٫ Detection the most Prevalent mutations in G6PD gene in Gilan and Golestan Provinees of Iran, Noori Dalooii M.R., Najafi L., Hajebrahimi Z., Mohammad Ganji and Sanati M.H.,۲nd Iranian congress of Genetic Disorders & Disabilities, December 2002,Tehran, Iran

۳۵٫ Investigation of mtDNA haplogroups and disease (Report from Iran(

Houshmand M., sharifpanah F., Alemohamad A., Rahmani M., Joughedost S.,Babrzadeh F., Vakilian M., Sanati M.H.,۲nd Iranian Congress of Genetic Disorders &C Disabilities, December 2002,Tehran, Iran.

۳۶٫  Detection of mutation In Iranian deaf families.,Salehi tabar R., Sanati M.H., Elahi E., Houshmand M., ۲nd Iranian Congress of Genetic Disorders &C Disabi Lities, December 2002,Tehran, Iran

۳۷٫ Biochemical and Molecular Diagnosis of Galactosemia,

Naghibzadeh Tabatabaee N., Houshmand M., Zare sh., Talachian Z., Majd I.,Sanati M.H., Mirzajani F., ۲nd Iranian congress of Genetic Disorders and Disabilives December 2002,Tehran, Iran

۳۸- Cloning and expression of human gamma- interferon cDNA in Ecoli., Fatemeh Alasti and M.H. Sanati (2003) third national congress of biotechnology, Mashhad, Iran.

 

۳۹- The molecular biology aspects of recessive hearing loss in Iranian population, Fatemeh Alasti and M.H. Sanati, (2003) 8th Iranian Genetics Congress, Tehran, Iran.

 

۴۰- Polymorphisms of Apolipoprotein E: Association with Susceptibility and Severity of Multiple Sclerosis., V.Hadavi, D.D.Farhud, M.H. sanati, M.Hushmand,S.M.Nabavi, M.Seyedian, M.Younesian (2004) The American Society of Human Genetics 54th Annual Meeting

۴۱P53 Polymorphism in Iranian Population with Four Different Ethnicity and incidence Pattern of Esophageal Cancer. S.Tanhaei, F.Biramijamal, M. H. Sanati, M. Sheidai. The 3rd Regional Conference of Asian Pacific Organization for Cancer Prevention (APOCP) GI Cancer Control.April 2005.Zibakenar, Rasht,Iran.

۴۲-Is Genetic Polymorphism at GST-P1 Locus Associate With Type of P53 Gene Mutation in Esophageal Squamous Cell Carcinoma from Iran?

 F.Biramijamal, M.H.Sanati, G.Iravanloo, N. Saligheh Araghi, S.Tanhaei, R.Sharifi,

A.Allameh, The 3rd Regional Conference of Asian Pacific Organization for Cancer Prevention (APOCP) GI Cancer Control.April 2005.Zibakenar, Rasht,Iran.

۴۳-Investigation of P53 Polymorphisms among Iranian Esophageal Squamous Cell Carcinoma from to find its role in Developing cancer.

N. Saligheh Araghi, F.Biramijamal, M.H.Sanati, G.Iravanloo, S.Tanhaei, B. Bayat, M.M Banoei. The 3rd Regional Conference of Asian Pacific Organization for Cancer Prevention (APOCP) GI Cancer Control.April 2005.Zibakenar, Rasht,Iran.

۴۴-Structure Study of human growth hormone: A thermodynamic and spectroscopic Approch”,

 M.S. Atri, M. Rezaei- tavirani, M. H. Sanati, A.A. Saboury and A. A. Moosavi- Movahed, 49th Annual Meeting of Biophysical Socity, Long Beach, California, USA ( 12- 16 Feb.2005).

۴۵- Thermodynamics of binding some metal ions on human growth hormone

A.A. Saboury, M.S. Atri, M. Kordbacheh, H. Ghourchaei and M.H. Sanati, 30th FEBS Conference & 9th IUBMB Conference, Budapest, Hungary(2-7 July 2005)

۴۶- “Spectroscopy, calorimetry and potentiometry study on the interaction of human growth hormone with copper ion”, M.Kordbacheh, S. Safarian, F.Mizani, M.H.Sanati, M. Shamsipur, B. Yakhchali and A.A. Moosavi- Movahedi, Sixth Iranian Biophysical Chemistry Conferencer, Damghan University of Basic Science, Damghan ( sept. 7-9, 2004).

۴۷- Is P53 gene polymorphism associated with multiple sclerosis in iran?

M. Sanati, F. Biramijamal, B. Bayat, M. Banoei. ESHG, Prague congress center( May 7-10.2005)

۴۸٫ Genetic polymorphism analysis of p53 in Iranian population with three different ethnicity and incidence pattern of Esophageal cancer. S. Tanhaei. F. Biramijamal. M. Sanati. ESHG, Prague congress center( May 7-10.2005)

۴۹٫ Strategic Planning for Prevention and Management of Genetic Disorders in Developing Countries, Mohemmed Hossein Sanati, Oral presentation as an invited speaker, The Thirteenth International Biotechnology Symposium and Exhibition, IBS-2008, 12-17 Oct. 2008, Dalian, China.

۵۰٫ Controlled Fabrication of Gelatin Nanoparticla as Drug Carriers, M. Jahanshahi, M.H. Sanati, Z. Minuchehr, S. Hajizadeh and Babaei, Nanotechnology and Its Applications, First Sharjah International Conference on Nanotechnology and Its Application, Sharjah, United arab Emirates, 10-12 April 2007.

۵۱٫ Genetic of Multiple Sclerosis, Mohammad Hossein Sanati, 7th International Congress of Multiple Sclerosis, 4-5 Nov., 2010, Imam Khomaini Hospital, Tehran, Iran.

۵۲٫ Genetics of Hearing Impairement, Mohammah Hossein Sanati, 4th Annual Iranian Neurogenetic Congress Advances in Neurogenetics, 24-26 Nov. 2010, Tehran, Iran.

۵۳٫ Recombinant human coagulation factor IX transgenic goats produced by transfer of nuclei from transfected fetal fibroblast, Goorabi H., Sanati M.H. et all, 11th Iranian Genetic Congress, 22-24 May 2010, Tehran, Iran.